Ugdh^lzme
Chemically induced Allele Detail

Summary

• Symbol: Ugdh^lzme
• Name: UDP-glucose dehydrogenase; lazy mesoderm
• MGI ID: MGI:2678264
• Gene: Ugdh Location: Chr5:65570550-65593185 bp, - strand Genetic Position: Chr5, 33.67 cM
• Alliance: Ugdh^lzme page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A new splice acceptor site was generated by a point mutation (T-to-G) 7 nt of upstream of exon 8. The mutation results in the incorporation of 6 nt (2 codons; FQ) into the transcribed mRNA between exon 7 (Q302) and 8 (V303). (J:85651)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ugdh Mutation: 34 strains or lines available

References

• Original: J:85651 Garcia-Garcia MJ, et al., Essential role of glycosaminoglycans in Fgf signaling during mouse gastrulation. Cell. 2003 Sep 19;114(6):727-37
• All: 2 reference(s)