Mnt^tm1Phu
Targeted Allele Detail

Summary

• Symbol: Mnt^tm1Phu
• Name: max binding protein; targeted mutation 1, Peter J Hurlin
• MGI ID: MGI:2678321
• Synonyms: Mnt^cko, Mnt^flox
• Gene: Mnt Location: Chr11:74721746-74736551 bp, + strand Genetic Position: Chr11, 45.76 cM, cytoband B-C
• Alliance: Mnt^tm1Phu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:85481
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted in introns 3 and 6 thus flanking exons 4 through 6. In addition, a Hygro selection cassette was placed in intron 3 between the loxP site and the start of exon 4. (J:85481)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mnt Mutation: 26 strains or lines available

References

• Original: J:85481 Hurlin PJ, et al., Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis. EMBO J. 2003 Sep 15;22(18):4584-96
• All: 3 reference(s)