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Ect2Gt(pT1ATGBetageo)1Ruiz
Gene trapped Allele Detail
Summary
Symbol: Ect2Gt(pT1ATGBetageo)1Ruiz
Name: ect2 oncogene; gene trap 1, Patricia Ruiz
MGI ID: MGI:2678389
Gene: Ect2  Location: Chr3:27151371-27207971 bp, - strand  Genetic Position: Chr3, 10.82 cM, cytoband B
Alliance: Ect2Gt(pT1ATGBetageo)1Ruiz page
Mutation
origin
Mutant Cell Line:  F045D05
Germline Transmission:  Earliest citation of germline transmission: J:85162
Parent Cell Line:  TBV2 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pT1ATGbetageo
 
Mutation detailsThe endogenous locus was disrupted by the insertion of a gene trap vector containing a splice acceptor site followed by Beta-geo and a polyadenylation signal. (J:85162)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ect2 Mutation:  56 strains or lines available
Notes
Information submitted to the NCBI Genome Survey Sequences Database (dbGSS) by the German Genetrap Consortium (GGTC) for gene trap cell line F045D05 gives R1 as the ES cell line used to create this allele. The original publication reporting large scale production of gene trap clones using four gene trap vectors says that ES cell-derived chimeras were produced using three ES cell lines (E14.1 (129P2/OlaHsd), R1 ((129X1/SvJ x 129S1/Sv)F1-Kitl+), TBV2 (129S2/SvPas)). GGTC records currently say that TBV2 ES cells were used to generate this allele. Chimeric mice were subsquently bred to C57BL/6 females.
References
Original:  J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory