Cbx1^{Gt(U3Betageo)1Ruiz}
Gene trapped Allele Detail

Summary

• Symbol: Cbx1^{Gt(U3Betageo)1Ruiz}
• Name: chromobox 1; gene trap 1, Patricia Ruiz
• MGI ID: MGI:2678420
• Gene: Cbx1 Location: Chr11:96679953-96699466 bp, + strand Genetic Position: Chr11, 60.11 cM
• Alliance: Cbx1^{Gt(U3Betageo)1Ruiz} page

Mutation origin

• Mutant Cell Line: M019D01
• Germline Transmission: Earliest citation of germline transmission: J:85162
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: U3betageo
• Mutation details: The endogenous locus was disrupted by the insertion of retroviral gene trap vector containing Beta-geo. The vector lacked a splice acceptor and therefore putatively inserted within an exon. (J:85162)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  M019D01	BZ690435 ; (MGI Seq Detail)	5' RACE	Chr11:96679962-96680178 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  229 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cbx1 Mutation: 91 strains or lines available

Notes

The German Genetrap Consortium mutant ES cell line M019D01 was used to generate this allele.

References

• Original: J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
• All: 2 reference(s)