Zfp423^{Gt(pT1Betageo)1Ruiz}
Gene trapped Allele Detail

Summary

• Symbol: Zfp423^{Gt(pT1Betageo)1Ruiz}
• Name: zinc finger protein 423; gene trap 1, Patricia Ruiz
• MGI ID: MGI:2678434
• Gene: Zfp423 Location: Chr8:88388438-88686223 bp, - strand Genetic Position: Chr8, 42.29 cM, cytoband C4
• Alliance: Zfp423^{Gt(pT1Betageo)1Ruiz} page

Mutation origin

• Mutant Cell Line: W008G09
• Germline Transmission: Earliest citation of germline transmission: J:85162
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The endogenous locus was disrupted by the insertion of a gene trap vector containing a splice acceptor site followed by Beta-geo and a polyadenylation signal. (J:85162)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  CL210542	CL210542 ; (MGI Seq Detail)	5' RACE	Chr8:88585911-88685873 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  439 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Zfp423 Mutation: 274 strains or lines available

Notes

Chimeric mice were subsquently bred to C57BL/6 females.

References

• Original: J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
• All: 1 reference(s)