Aqr^{Gt(pT1Betageo)1Ruiz}
Gene trapped Allele Detail

Summary

• Symbol: Aqr^{Gt(pT1Betageo)1Ruiz}
• Name: aquarius; gene trap 1, Patricia Ruiz
• MGI ID: MGI:2678463
• Gene: Aqr Location: Chr2:113931642-114005788 bp, - strand Genetic Position: Chr2, 57.57 cM, cytoband E5-F2
• Alliance: Aqr^{Gt(pT1Betageo)1Ruiz} page

Mutation origin

• Mutant Cell Line: W078A08
• Germline Transmission: Earliest citation of germline transmission: J:85162
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pT1betageo
• Mutation details: The endogenous locus was disrupted by the insertion of a gene trap vector containing a splice acceptor site followed by Beta-geo and a polyadenylation signal. (J:85162)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  W078A08	BZ689930 ; (MGI Seq Detail)	5' RACE	Chr2:113967350-113973576 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  10 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Phenotypes

Key:

hm	homozygous	ht	heterozygous	tg	involves transgenes	√	phenotype observed
cn	conditional genotype	cx	complex: > 1 genome feature	ot	other: hemizygous, indeterminate,...	N	normal phenotype

Genotype/
Background:

	Allelic Composition	Genetic Background	Cell Line(s)
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hm1	Aqr^Gt(pT1Betageo)1Ruiz/Aqr^Gt(pT1Betageo)1Ruiz	involves: 129S2/SvPas * C57BL/6

Phenotypes:

Affected Systems	hm1
show or hide all annotated terms
normal phenotype	√
no abnormal phenotype detected	√

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aqr Mutation: 66 strains or lines available

References

• Original: J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
• All: 1 reference(s)