Mtf2^{Gt(U3Betageo)1Ruiz}
Gene trapped Allele Detail

Summary

• Symbol: Mtf2^{Gt(U3Betageo)1Ruiz}
• Name: metal response element binding transcription factor 2; gene trap 1, Patricia Ruiz
• MGI ID: MGI:2678466
• Synonyms: Pcl2^GT
• Gene: Mtf2 Location: Chr5:108213540-108256870 bp, + strand Genetic Position: Chr5, 52.41 cM
• Alliance: Mtf2^{Gt(U3Betageo)1Ruiz} page

Mutation origin

• Mutant Cell Line: M016A06
• Germline Transmission: Earliest citation of germline transmission: J:85162
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: U3betageo
• Mutation details: The endogenous locus was disrupted by the insertion of retroviral gene trap vector containing Beta-geo inserted into exon 3. (J:85162)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  M016A06	CL211497 ; (MGI Seq Detail)	5' RACE	Chr5:108228841-108229041 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  759 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mtf2 Mutation: 314 strains or lines available

Notes

This allele was generated from The German Genetrap Consortium mutant ES cell line M016A06.

References

• Original: J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
• All: 2 reference(s)