About   Help   FAQ
Camltm1Rjb
Targeted Allele Detail
Summary
Symbol: Camltm1Rjb
Name: calcium modulating ligand; targeted mutation 1, Richard J Bram
MGI ID: MGI:2678819
Synonyms: CAML-
Gene: Caml  Location: Chr13:55770818-55780224 bp, + strand  Genetic Position: Chr13, 30.06 cM
Alliance: Camltm1Rjb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:85708
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAll of exon 1 and a 5' portion of exon 2 was replaced with a neomycin selection cassette inserted by homologous recombination. Protein was undetected by Western blot analysis of homozygous mutant ES cells. (J:85708)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Caml Mutation:  25 strains or lines available
References
Original:  J:85708 Tran DD, et al., CAML is required for efficient EGF receptor recycling. Dev Cell. 2003 Aug;5(2):245-56
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory