Ikbkg^tm1.1Mpa
Targeted Allele Detail

Summary

• Symbol: Ikbkg^tm1.1Mpa
• Name: inhibitor of kappaB kinase gamma; targeted mutation 1.1, Manolis Pasparakis
• MGI ID: MGI:2679024
• Synonyms: Nemo^F, Nemo^FL
• Gene: Ikbkg Location: ChrX:73436896-73497460 bp, + strand Genetic Position: ChrX, 38.0 cM
• Alliance: Ikbkg^tm1.1Mpa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:63055
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 2 was left flanked by single loxP sites in introns 1 and 2. (J:63055)

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ikbkg Mutation: 16 strains or lines available

References

• Original: J:63055 Schmidt-Supprian M, et al., NEMO/IKK gamma-deficient mice model incontinentia pigmenti. Mol Cell. 2000 Jun;5(6):981-92
• All: 52 reference(s)