Tg(Tnnt2-cre)5Blh
Transgene Detail

Summary

• Symbol: Tg(Tnnt2-cre)5Blh
• Name: transgene insertion 5, Brigid L Hogan
• MGI ID: MGI:2679081
• Synonyms: cTnt-Cre, cTntCre, Tnnt2-Cre, TNT-Cre
• Transgene: Tg(Tnnt2-cre)5Blh Location: unknown
• Alliance: Tg(Tnnt2-cre)5Blh page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Tnnt2-cre)5Blh expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Tnnt2 (24837)

  Tnnt2

  (MGI:104597)

• Mutation details: Sequence encoding cre recombinase was adjoined to the rat troponin T2 promoter. The promoter drove expression of cre recombinase in the cardiomyocyte lineage beginning at E7.5. Expression was observed in all myocardium at E10.5. (J:86001, J:175042)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tnnt2 (rat) Summary of all recombinase alleles driven by Tnnt2. Comparative matrix view of recombinase activities Alliance rat Tnnt2 gene page

Disease models

Expression

In Mice Carrying this Mutation:

226 assay results 12 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:86001 Jiao K, et al., An essential role of Bmp4 in the atrioventricular septation of the mouse heart. Genes Dev. 2003 Oct 1;17(19):2362-7
• All: 91 reference(s)