Pitpnm2^tm1Tili
Targeted Allele Detail

Summary

• Symbol: Pitpnm2^tm1Tili
• Name: phosphatidylinositol transfer protein, membrane-associated 2; targeted mutation 1, Tiansen Li
• MGI ID: MGI:2679326
• Gene: Pitpnm2 Location: Chr5:124256753-124387823 bp, - strand Genetic Position: Chr5, 63.39 cM
• Alliance: Pitpnm2^tm1Tili page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:85900
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region included approximately half of the PITP homology domain. Protein was undetected by Western blot analysis of retinal extracts obtained from homozygous mutant mice. (J:85900)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pitpnm2 Mutation: 47 strains or lines available

References

• Original: J:85900 Lu C, et al., The mammalian retinal degeneration B2 gene is not required for photoreceptor function and survival. Neuroscience. 2001;107(1):35-41
• All: 1 reference(s)