Kntc1^jgl
Spontaneous Allele Detail

Summary

• Symbol: Kntc1^jgl
• Name: kinetochore associated 1; jagged tail-like
• MGI ID: MGI:2679537
• Gene: Kntc1 Location: Chr5:123887779-123959656 bp, + strand Genetic Position: Chr5, 63.17 cM
• Alliance: Kntc1^jgl page

Kntc1^jgl/Kntc1^jgl

Show the 4 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: BALB/cByJ-Clcn1^adr-mto2J

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: Similar to jg in phenotype and map location. However, a complementation test was not performed because mice carrying jg were not available except by recovery from cryopreservation. A C-to-T point mutation at coding nucleotide 2596 of the cDNA (NM_001042421) results in premature truncation at position 866 of the encoded protein (p.R866*). (J:222308)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kntc1 Mutation: 111 strains or lines available

References

• Original: J:85852 Harris BS, et al., A kinked tail mutation on Mouse Chromosome 5 named jagged tail-like. Mouse Mutant Resources Web Site, The Jackson Laboratory, Bar Harbor, Maine. MGI Direct Data Submission. 2003
• All: 2 reference(s)