Id3^tm1Zhu
Targeted Allele Detail

Summary

• Symbol: Id3^tm1Zhu
• Name: inhibitor of DNA binding 3; targeted mutation 1, Yuan Zhuang
• MGI ID: MGI:2679967
• Synonyms: Id3-
• Gene: Id3 Location: Chr4:135871133-135872703 bp, + strand Genetic Position: Chr4, 68.34 cM
• Alliance: Id3^tm1Zhu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:56950
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The first 2 exons and part of exon 3 were replaced by a PGK neomycin cassette. Gene disruption was confirmed by Northern blot analysis. (J:56950)

Disease models

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Id3 Mutation: 16 strains or lines available

References

• Original: J:56950 Pan L, et al., Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene. Mol Cell Biol. 1999 Sep;19(9):5969-80
• All: 59 reference(s)