Iglc1^tm1.1Ust
Targeted Allele Detail

Summary

• Symbol: Iglc1^tm1.1Ust
• Name: immunoglobulin lambda constant 1; targeted mutation 1.1, Ursula Storb
• MGI ID: MGI:2680013
• Synonyms: Igl^tm1.1Ust, S
• Gene: Iglc1 Location: Chr16:18880502-18880821 bp, - strand Genetic Position: Chr16, 11.8 cM
• Alliance: Iglc1^tm1.1Ust page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:68144
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: This allele is a derivative of Igl^tm1Ust in which the loxP-flanked neomycin selection cassette was removed through Cre-mediated recombination. A single loxP site remains in the place of the insertion. (J:68144)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Iglc1 Mutation: 4 strains or lines available

References

• Original: J:68144 Sun T, et al., Insertion of phosphoglycerine kinase (pgk)-neo 5' of jlambda1 dramatically enhances vjlambda1 rearrangement. J Exp Med. 2001 Mar 19;193(6):699-712
• All: 1 reference(s)