Tg(Ins2-HA)165Bri
Transgene Detail

Summary

• Symbol: Tg(Ins2-HA)165Bri
• Name: transgene insertion 165, Ralph Brinster
• MGI ID: MGI:2680173
• Synonyms: 2917-5, Ins-HA, InsHA, RIP-HA, Tg(Ins-2,HA)Bri165
• Transgene: Tg(Ins2-HA)165Bri Location: unknown
• Alliance: Tg(Ins2-HA)165Bri page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The transgenic construct consisted of the rat insulin 2 promoter fused to sequence encoding influenza hemagglutinin (HA) followed by the 3' untranslated region and polyadenylation signal from the H2-Ea. HA was from influenza A/PR/8/34. This rat insulin 2 promoter is active in pancreatic beta-cells. (J:86430)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available

References

• Original: J:86430 Lo D, et al., Peripheral tolerance to an islet cell-specific hemagglutinin transgene affects both CD4+ and CD8+ T cells. Eur J Immunol. 1992 Apr;22(4):1013-22
• All: 23 reference(s)