Pla2g12b^hlb218
Chemically induced Allele Detail

Summary

• Symbol: Pla2g12b^hlb218
• Name: phospholipase A2, group XIIB; heart, lung and blood, 218
• MGI ID: MGI:2680455
• Gene: Pla2g12b Location: Chr10:59239482-59257798 bp, + strand Genetic Position: Chr10, 29.54 cM, cytoband B3
• Alliance: Pla2g12b^hlb218 page

Increased liver lipid level in Pla2g12b^hlb218/Pla2g12b^hlb218 mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

Allele Type: Chemically induced (ENU) Mutation: Single point mutation Mutation details: ENU induced a G to A transition in exon 3 resulting in a cysteine to tyrosine mutation at position 129 (C129Y). (J:187708) Inheritance: Recessive

Identification of the mutation in the Pla2g12b^hlb218 allele

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pla2g12b Mutation: 17 strains or lines available

References

• Original: J:82961 JAX National Heart, Lung and Blood Program for Genomic Applications (PGA), Heritable mouse mutants from the JAX NHLBI ENU Mutagenesis Program. MGI Direct Data Submission. 2003-10
• All: 3 reference(s)