Tg(Camk2a-cre)2834Lusc
Transgene Detail

Summary

• Symbol: Tg(Camk2a-cre)2834Lusc
• Name: transgene insertion 2834, Bernhard Luscher
• MGI ID: MGI:2680625
• Synonyms: (CaMKII)Cre2834, CaMKIICre2834
• Transgene: Tg(Camk2a-cre)2834Lusc Location: unknown
• Alliance: Tg(Camk2a-cre)2834Lusc page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Camk2a-cre)2834Lusc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Camk2a

• Mutation details: Sequence encoding cre recombinase was adjoined to 8.5 kb of the Camk2a promoter. Cre expressionr was observed in the hippocampus beginning at postnatal day 17. Expression levels gradually increased through postnatal day 34 and the expression pattern expanded to include other forebrain regions. Expression was undetected in the hindbrain. (J:86221)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Camk2a (species not specified) Summary of all recombinase alleles driven by Camk2a. Comparative matrix view of recombinase activities

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:86221 Schweizer C, et al., The gamma2 subunit of GABA(A) receptors is required for maintenance of receptors at mature synapses. Mol Cell Neurosci. 2003 Oct;24(2):442-50
• All: 16 reference(s)