Dlg1^{Gt(gt1.8geo)1Ber}
Gene trapped Allele Detail

Summary

• Symbol: Dlg1^{Gt(gt1.8geo)1Ber}
• Name: discs large MAGUK scaffold protein 1; gene trap 1, Alan Bernstein
• MGI ID: MGI:2680670
• Synonyms: dlg^gt, GT-dlg1
• Gene: Dlg1 Location: Chr16:31482261-31692174 bp, + strand Genetic Position: Chr16, 22.4 cM
• Alliance: Dlg1^{Gt(gt1.8geo)1Ber} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:67360
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Hypomorph, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap vector inserted into a position corresponding to 1653 of the encoded transcript. A fusion transcript that encodes part of the endogenous protein fused to beta-galactosidase is expressed from this allele. (J:67360)

Expression

In Mice Carrying this Mutation:	78 assay results
In Structures Affected by this Mutation:	10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dlg1 Mutation: 76 strains or lines available

References

• Original: J:67360 Caruana G, et al., Craniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large gene. Mol Cell Biol. 2001 Mar;21(5):1475-83
• All: 7 reference(s)