Osmr^tm1Mtan
Targeted Allele Detail

Summary

• Symbol: Osmr^tm1Mtan
• Name: oncostatin M receptor; targeted mutation 1, Minoru Tanaka
• MGI ID: MGI:2680723
• Synonyms: OSMR^-, OSMRbeta^-
• Gene: Osmr Location: Chr15:6843049-6904434 bp, - strand Genetic Position: Chr15, 3.3 cM
• Alliance: Osmr^tm1Mtan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:86261
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A cassette containing lacZ and neo was inserted at the start codon of the endogenous locus. Transcript was undetected in homozygous mutant mice by Northern blot analysis of lung RNA. (J:86261)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Osmr Mutation: 58 strains or lines available

References

• Original: J:86261 Tanaka M, et al., Targeted disruption of oncostatin M receptor results in altered hematopoiesis. Blood. 2003 Nov 1;102(9):3154-62
• All: 27 reference(s)