Krt71^Rgsc689
Chemically induced Allele Detail

Summary

• Symbol: Krt71^Rgsc689
• Name: keratin 71; RIKEN Genomic Sciences Center (GSC), 689
• MGI ID: MGI:2681099
• Synonyms: Krt2-6g^1Rgsc, M100689
• Gene: Krt71 Location: Chr15:101642384-101651532 bp, - strand Genetic Position: Chr15, 57.0 cM
• Alliance: Krt71^Rgsc689 page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: RIKEN GSC ENU Project

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: Sequence analysis of Krt2-6g in this mouse identified the transversion of an thymine to a guanine at nucleotide 1271, resulting in a leucine to tryptophan missense mutation at codon 424 (L424W). (J:86407)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Krt71 Mutation: 43 strains or lines available

References

• Original: J:86407 Kikkawa Y, et al., A small deletion hotspot in the type II keratin gene mK6irs1/Krt2-6g on mouse chromosome 15, a candidate for causing the wavy hair of the caracul (Ca) mutation. Genetics. 2003 Oct;165(2):721-33
• All: 2 reference(s)