Tg(EF1A-Cdc7)DKO28Hmas
Transgene Detail

Summary

• Symbol: Tg(EF1A-Cdc7)DKO28Hmas
• Name: transgene insertion DKO28, Hisao Masai
• MGI ID: MGI:2681165
• Transgene: Tg(EF1A-Cdc7)DKO28Hmas Location: unknown
• Alliance: Tg(EF1A-Cdc7)DKO28Hmas page

Transgene origin

• Strain of Origin: 129S/SvEv-Gpi1^c

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(EF1A-Cdc7)DKO28Hmas expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cdc7 (MGI:1309511)

• Mutation details: The transgene construct contained the human EF1A promoter driving a murine Cdc7 cDNA linked to a PGK-puromycin resistance cassete and flanked by loxP sites. Following this is a promoterless EGFP gene. (J:76497)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:76497 Kim JM, et al., Inactivation of Cdc7 kinase in mouse ES cells results in S-phase arrest and p53-dependent cell death. EMBO J. 2002 May 1;21(9):2168-79
• All: 2 reference(s)