Birc5^tm1Vaux
Targeted Allele Detail

Summary

• Symbol: Birc5^tm1Vaux
• Name: baculoviral IAP repeat-containing 5; targeted mutation 1, David L Vaux
• MGI ID: MGI:2681348
• Synonyms: survivin^-
• Gene: Birc5 Location: Chr11:117740077-117746569 bp, + strand Genetic Position: Chr11, 82.96 cM, cytoband E2
• Alliance: Birc5^tm1Vaux page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:86384
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding region except for the first 4 codons was replaced with a cassette containing lacZ followed by floxed neo. (J:86384)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Birc5 Mutation: 20 strains or lines available

References

• Original: J:86384 Uren AG, et al., Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype. Curr Biol. 2000 Nov 2;10(21):1319-28
• All: 1 reference(s)