Slc45a2^tm1(K14-A)R
Targeted Allele Detail

Summary

• Symbol: Slc45a2^tm1(K14-A)R
• Name: solute carrier family 45, member 2; targeted mutation 1, Oak Ridge National Laboratory
• MGI ID: MGI:2681497
• Synonyms: In(15)21Rk Matp^tm1(K14-A)R, In(15)21Rk-Matp^{+tm(k14-Agouti)1R}, LE21Rk
• Gene: Slc45a2 Location: Chr15:11000807-11029319 bp, + strand Genetic Position: Chr15, 5.4 cM
• Alliance: Slc45a2^tm1(K14-A)R page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:91142
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: mixed

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Insertion
• Mutation details: A PGK-neomycin-K14-Agouti minigene cassette was inserted in intron 2 of the Matp gene within the inverted region of In(15)21Rk. (J:91142)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc45a2 Mutation: 55 strains or lines available

Notes

ES cells used were derived from double heterozygous mice carrying both In(15)21RK and Matp ^+/uw crossed to 129X1/SvJ males. Genetic background thus includes C57BL/6, DBA/2J, and 129X1/SvJ. The ES cell line used was male.

References

• Original: J:91142 Chick WS, et al., Modification of an existing chromosomal inversion to engineer a balancer for mouse chromosome 15. Genetics. 2004 Jun;167(2):889-95
• All: 1 reference(s)