Gtpbp2^nmf205
Chemically induced Allele Detail

Summary

• Symbol: Gtpbp2^nmf205
• Name: GTP binding protein 2; neuroscience mutagenesis facility, 205
• MGI ID: MGI:2681955
• Gene: Gtpbp2 Location: Chr17:46471958-46480296 bp, + strand Genetic Position: Chr17, 22.89 cM, cytoband C-D
• Alliance: Gtpbp2^nmf205 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: This ENU-induced T to C point mutation in the consensus splice donor site of intron 6 results in misspliced mRNAs with premature stop codons. Western blot analysis failed to detect this protein in cerebellar extracts from homozygotes. (J:211326)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:

104036 assay results 3 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gtpbp2 Mutation: 38 strains or lines available

References

• Original: J:82238 JAX Neuroscience Mutagenesis Facility, Heritable mouse mutants from JAX NMF ENU Mutagenesis Program. MGI Direct Data Submission. 2003
• All: 6 reference(s)