Egfr^Mhdadsk5
Chemically induced Allele Detail

Summary

• Symbol: Egfr^Mhdadsk5
• Name: epidermal growth factor receptor; Martin Hrabe de Angelis dark skin 5
• MGI ID: MGI:2682255
• Synonyms: Egfr^Dsk5
• Gene: Egfr Location: Chr11:16702203-16868158 bp, + strand Genetic Position: Chr11, 9.41 cM, cytoband A1-A4
• Alliance: Egfr^Mhdadsk5 page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation was identified as an T to A transversion causing a missense mutation that predicts a Leu863Gln substitution in tyrosine kinase domain. (J:81301)
• Inheritance: Dominant

Disease models

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Egfr Mutation: 87 strains or lines available

References

• Original: J:81301 Fitch KR, et al., Genetics of dark skin in mice. Genes Dev. 2003 Jan 15;17(2):214-28
• All: 10 reference(s)