Nanos3^tm1Ysa
Targeted Allele Detail

Summary

• Symbol: Nanos3^tm1Ysa
• Name: nanos C2HC-type zinc finger 3; targeted mutation 1, Yumiko Saga
• MGI ID: MGI:2682607
• Synonyms: nanos3-L
• Gene: Nanos3 Location: Chr8:84900359-84911396 bp, - strand Genetic Position: Chr8, 40.45 cM
• Alliance: Nanos3^tm1Ysa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:86522
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A lacZ cassette was inserted at the start codon of the first coding exon. A floxed neo cassette was inserted downstream of the coding region and was subsequently removed via cre mediated recombination. LacZ expression was detected in mutant mice. (J:86522)

Expression

In Mice Carrying this Mutation:	2 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nanos3 Mutation: 28 strains or lines available

References

• Original: J:86522 Tsuda M, et al., Conserved role of nanos proteins in germ cell development. Science. 2003 Aug 29;301(5637):1239-41
• All: 10 reference(s)