Sox18^Mhdadcc1
Chemically induced Allele Detail

Summary

• Symbol: Sox18^Mhdadcc1
• Name: SRY (sex determining region Y)-box 18; Martin Hrabe de Angelis dark coat color 1
• MGI ID: MGI:2682755
• Synonyms: Dcc1, Sox18^Gsfdcc1
• Gene: Sox18 Location: Chr2:181311630-181313433 bp, - strand Genetic Position: Chr2, 103.71 cM
• Alliance: Sox18^Mhdadcc1 page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation was identified as a T to A transversion that results in a nonsense mutation, Leu220ter, in the transactivation domain of the protein. (J:81301)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox18 Mutation: 26 strains or lines available

References

• Original: J:81301 Fitch KR, et al., Genetics of dark skin in mice. Genes Dev. 2003 Jan 15;17(2):214-28
• All: 1 reference(s)