Smarca5^tm1.1Ais
Targeted Allele Detail

Summary

• Symbol: Smarca5^tm1.1Ais
• Name: SNF2 related chromatin remodeling ATPase 5; targeted mutation 1.1, Art I Skoultchi
• MGI ID: MGI:2683166
• Gene: Smarca5 Location: Chr8:81426572-81466088 bp, - strand Genetic Position: Chr8, 38.41 cM
• Alliance: Smarca5^tm1.1Ais page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:86695
• Parent Cell Line: WW6 (ES Cell)
• Strain of Origin: STOCK 129/Sv and C57BL/6J and SJL

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A single loxP site was left in place of a genomic fragment encompassing exons 5 through 9a after the floxed neo cassette was excised via cre mediated recombination. The deleted region encoded the catalytic ATPase domain (DEXDc). (J:86695)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smarca5 Mutation: 50 strains or lines available

References

• Original: J:86695 Stopka T, et al., The ISWI ATPase Snf2h is required for early mouse development. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14097-102
• All: 3 reference(s)