Sp8^tm1Aman
Targeted Allele Detail

Summary

• Symbol: Sp8^tm1Aman
• Name: trans-acting transcription factor 8; targeted mutation 1, Ahmed Mansouri
• MGI ID: MGI:2684137
• Gene: Sp8 Location: Chr12:118810064-118816311 bp, + strand Genetic Position: Chr12, 63.48 cM
• Alliance: Sp8^tm1Aman page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:86325
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A sequence fragment from the 5' portion of exon 3 was replaced with a cassette containing lacZ and PGK-neo. (J:86325)

Expression

In Structures Affected by this Mutation:

12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sp8 Mutation: 29 strains or lines available

References

• Original: J:86325 Treichel D, et al., mBtd is required to maintain signaling during murine limb development. Genes Dev. 2003 Nov 1;17(21):2630-5
• All: 4 reference(s)