Slc27a4tm1Asta
Targeted Allele Detail
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Symbol: |
Slc27a4tm1Asta |
Name: |
solute carrier family 27 (fatty acid transporter), member 4; targeted mutation 1, Andreas Stahl |
MGI ID: |
MGI:2684501 |
Gene: |
Slc27a4 Location: Chr2:29692646-29707534 bp, + strand Genetic Position: Chr2, 20.64 cM, cytoband B
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Alliance: |
Slc27a4tm1Asta page
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Germline Transmission: |
Earliest citation of germline transmission:
J:86762
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S/SvEv
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutation: |
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Disruption caused by insertion of vector
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Mutation details: A genomic fragment encompassing exons 1 and 2 was replaced with a cassette containing nls-lacZ and PGK-neo. The deleted sequence encoded the first 185 amino acids of the protein. Heterozygous mutant mice were shown to have approximately half as much protein as wild-type mice by Western blot analysis.
(J:86762)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Slc27a4 Mutation: |
37 strains or lines available
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Original: |
J:86762 Gimeno RE, et al., Targeted deletion of fatty acid transport protein-4 results in early embryonic lethality. J Biol Chem. 2003 Dec 5;278(49):49512-6 |
All: |
1 reference(s) |
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