Abcg5^tm1Plo
Targeted Allele Detail

Summary

• Symbol: Abcg5^tm1Plo
• Name: ATP binding cassette subfamily G member 5; targeted mutation 1, Torsten Ploesch
• MGI ID: MGI:2687002
• Synonyms: Abcg5^-
• Gene: Abcg5 Location: Chr17:84965662-84990439 bp, - strand Genetic Position: Chr17, 55.02 cM
• Alliance: Abcg5^tm1Plo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:87209
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The endogenous locus was disrupted by the insertion of a cassette containing beta galactosidase and neo into exon 3. The insertion deleted 87 bp. (J:87209)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Abcg5 Mutation: 48 strains or lines available

References

• Original: J:87209 Plosch T, et al., Sitosterolemia in ABC-Transporter G5-deficient mice is aggravated on activation of the liver-X receptor. Gastroenterology. 2004 Jan;126(1):290-300
• All: 8 reference(s)