Rere^om
Chemically induced Allele Detail

Summary

• Symbol: Rere^om
• Name: arginine glutamic acid dipeptide (RE) repeats; openmind
• MGI ID: MGI:2687072
• Synonyms: Atn2^om, Atr2L
• Gene: Rere Location: Chr4:150366103-150706423 bp, + strand Genetic Position: Chr4, 81.34 cM
• Alliance: Rere^om page

Severe microphthalmia in Rere^eyes3/Rere^om mice

Show the 5 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: BTBR

Mutation description

Allele Type: Chemically induced (ENU) Mutation: Single point mutation Mutation details: This allele is a single base change from T to A in the exon 4 splice donor. This results in a primary product in which exon 4 is deleted as well as a minor product with both exons 4 and 5 deleted. In either case, a frame shift results and mRNA transcript cannot be detected by whole mount in situ hybridization. An mRNA that was approximately 70 bases shorter than normal could be detected by RT-PCR but only weakly. (J:87046)

Location and mutation in the ENU-induced Rere^om allele

Expression

In Mice Carrying this Mutation:	12 assay results
In Structures Affected by this Mutation:	14 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rere Mutation: 212 strains or lines available

References

• Original: J:87046 Zoltewicz JS, et al., Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis. Development. 2004 Jan;131(1):3-14
• All: 9 reference(s)