Ednra^tm2Ywa
Targeted Allele Detail

Summary

• Symbol: Ednra^tm2Ywa
• Name: endothelin receptor type A; targeted mutation 2, Masashi Yanagisawa
• MGI ID: MGI:2687362
• Synonyms: Ednra^fl, ETA^flox
• Gene: Ednra Location: Chr8:78389658-78451081 bp, - strand Genetic Position: Chr8, 36.63 cM, cytoband C2
• Alliance: Ednra^tm2Ywa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:86476
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A genomic region encompassing exons 6, 7, and 8 were flanked by an upstream single loxP site and a downstream floxed neo cassette. (J:86476)

Expression

In Structures Affected by this Mutation:

12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ednra Mutation: 35 strains or lines available

References

• Original: J:86476 Kedzierski RM, et al., Cardiomyocyte-specific endothelin A receptor knockout mice have normal cardiac function and an unaltered hypertrophic response to angiotensin II and isoproterenol. Mol Cell Biol. 2003 Nov;23(22):8226-32
• All: 19 reference(s)