Efnb2^tm4Kln
Targeted Allele Detail

Summary

• Symbol: Efnb2^tm4Kln
• Name: ephrin B2; targeted mutation 4, Rudiger Klein
• MGI ID: MGI:3026687
• Synonyms: ephrinB2^fl, ephrinB2^lx
• Gene: Efnb2 Location: Chr8:8667434-8711242 bp, - strand Genetic Position: Chr8, 3.42 cM
• Alliance: Efnb2^tm4Kln page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:87398
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A 2.2 kb genomic fragment including exon 2 was flanked by single loxP sites. An frt-flanked neo cassette included in the targeting vector was excised via FLP-mediated recombination. (J:87398)

Expression

In Mice Carrying this Mutation:

3 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Efnb2 Mutation: 29 strains or lines available

References

• Original: J:87398 Grunwald IC, et al., Hippocampal plasticity requires postsynaptic ephrinBs. Nat Neurosci. 2004 Jan;7(1):33-40
• All: 34 reference(s)