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Cntnap1tm1Pele
Targeted Allele Detail
Summary
Symbol: Cntnap1tm1Pele
Name: contactin associated protein-like 1; targeted mutation 1, Elior Peles
MGI ID: MGI:3026869
Synonyms: Caspr-
Gene: Cntnap1  Location: Chr11:101065429-101081550 bp, + strand  Genetic Position: Chr11, 64.33 cM, cytoband D
Alliance: Cntnap1tm1Pele page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:87070
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a neomycin selection cassette inserted by homologous recombination. Protein was undetected in homozygous mutant mice by Western blot analysis of brain, spinal cord, and sciatic nerve samples. (J:87070)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cntnap1 Mutation:  56 strains or lines available
References
Original:  J:87070 Gollan L, et al., Caspr regulates the processing of contactin and inhibits its binding to neurofascin. J Cell Biol. 2003 Dec 22;163(6):1213-8
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory