Spon2tm1Mjb
Targeted Allele Detail
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| Symbol: |
Spon2tm1Mjb |
| Name: |
spondin 2, extracellular matrix protein; targeted mutation 1, Michael J Bevan |
| MGI ID: |
MGI:3026870 |
| Synonyms: |
Mindin -/- |
| Gene: |
Spon2 Location: Chr5:33370862-33375596 bp, - strand Genetic Position: Chr5, 17.5 cM
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| Alliance: |
Spon2tm1Mjb page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:87393
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| Parent Cell Line: |
TC1/TC-1 (ES Cell)
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| Strain of Origin: |
129S6/SvEvTac
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Part of exon 1 and all of exons 2 and 3 were replaced with a neomycin resistance gene. Absence of of mRNA was confirmed by RT-PCR and protein was undetectable in lymphnodes by immunoblot analysis.
(J:87393)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Spon2 Mutation: |
25 strains or lines available
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| Original: |
J:87393 He YW, et al., The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens. Nat Immunol. 2004 Jan;5(1):88-97 |
| All: |
8 reference(s) |
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Analysis Tools
