Nfya^tm1Mait
Targeted Allele Detail

Summary

• Symbol: Nfya^tm1Mait
• Name: nuclear transcription factor-Y alpha; targeted mutation 1, Sankar N Maity
• MGI ID: MGI:3027019
• Synonyms: B^flox
• Gene: Nfya Location: Chr17:48693917-48716782 bp, - strand Genetic Position: Chr17, 23.99 cM, cytoband C-D
• Alliance: Nfya^tm1Mait page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:87090
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A genomic fragment encompassing exons 3 through 8 was flanked by single loxP sites. The floxed sequence included exons 7 and 8 which encode the DNA binding and subunit interaction domains. (J:87090)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nfya Mutation: 81 strains or lines available

References

• Original: J:87090 Bhattacharya A, et al., The B subunit of the CCAAT box binding transcription factor complex (CBF/NF-Y) is essential for early mouse development and cell proliferation. Cancer Res. 2003 Dec 1;63(23):8167-72
• All: 11 reference(s)