Del(6Vmn1r40-Aldh1l1)1Anl
Radiation induced Allele Detail

Summary

• Symbol: Del(6Vmn1r40-Aldh1l1)1Anl
• Name: deletion, Chr 6, Argonne National Laboratory 1
• MGI ID: MGI:3027023
• Synonyms: aldh1l1-null, FDH(-/-), Mthfd1^neut2, NEUT2, neutron 2
• Gene: Del(6Vmn1r40-Aldh1l1)1Anl Location: Chr6:89688243-90576153 bp Genetic Position: Chr6, Syntenic

Mutation origin

• Strain of Origin: C57BL/6JAnl

Mutation description

• Allele Type: Radiation induced
• Mutations: Intergenic deletion, Intragenic deletion
• Del(6Vmn1r40-Aldh1l1)1Anl involves 35 genes/genome features (Vmn1r40, Vmn1r41, Vmn1r-ps26 ...) View all
• Mutation details: This mutation is a 841,250 bp deletion on chromosome 6, with one breakpoint within the Aldh1l1 gene. This deletion removes all but the last two exons of the Aldh1l1 gene, the entire 5 flanking genomic sequence (putative promoter region), as well as at le ast 27 other upstream genes (J:134595). Neither Aldh1l1 mRNA nor protein is detectable in mutant mice. No no detectable urocanase activity is seen in homozygous mutant mice. (J:21726, J:72944, J:134595)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(6Vmn1r40-Aldh1l1)1Anl Mutation: 0 strains or lines available

References

• Original: J:79621 Giometti CS, et al., Altered protein expression detected in the F1 offspring of male mice exposed to fission neutrons. Mutat Res. 1994 Jan;320(1-2):75-85
• All: 5 reference(s)