Ifi47^tm1Gat
Targeted Allele Detail

Summary

• Symbol: Ifi47^tm1Gat
• Name: interferon gamma inducible protein 47; targeted mutation 1, Gregory A Taylor
• MGI ID: MGI:3027113
• Gene: Ifi47 Location: Chr11:48967414-48987801 bp, + strand Genetic Position: Chr11, 29.08 cM, cytoband B1.2
• Alliance: Ifi47^tm1Gat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:87535
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding region was replaced with a neomycin selection cassette inserted by homologous recombination. Western blot analysis of splenic and thymic lysates indicated an absence of protein in homozygous mutant mice. (J:87535)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ifi47 Mutation: 25 strains or lines available

References

• Original: J:87535 Collazo CM, et al., Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection. J Exp Med. 2001 Jul 16;194(2):181-8
• All: 2 reference(s)