Rgs9bp^tm1Hels
Targeted Allele Detail

Summary

• Symbol: Rgs9bp^tm1Hels
• Name: regulator of G-protein signalling 9 binding protein; targeted mutation 1, Stefan Heller
• MGI ID: MGI:3028628
• Synonyms: R9AP-
• Gene: Rgs9bp Location: Chr7:35278418-35285007 bp, - strand Genetic Position: Chr7, 21.37 cM
• Alliance: Rgs9bp^tm1Hels page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:87582
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Other
• Mutation details: The entire, intronless, coding region was replaced with a cassette containing tau-lacZ and neo. Protein was undetected in the retinas of homozygous mutant mice by Western blot analysis. (J:87582)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rgs9bp Mutation: 6 strains or lines available

References

• Original: J:87582 Keresztes G, et al., Absence of the RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouse. J Biol Chem. 2004 Jan 16;279(3):1581-4
• All: 10 reference(s)