Ntsr2^tm1Hmno
Targeted Allele Detail

Summary

• Symbol: Ntsr2^tm1Hmno
• Name: neurotensin receptor 2; targeted mutation 1, Hiroshi Maeno
• MGI ID: MGI:3029205
• Gene: Ntsr2 Location: Chr12:16703477-16710223 bp, + strand Genetic Position: Chr12, 7.98 cM
• Alliance: Ntsr2^tm1Hmno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:87872
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A portion of exon 1, including the start codon, was replaced with a neomycin selection cassette inserted by homologous recombination. Transcript was undetected by RT-PCR analysis. (J:87872)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ntsr2 Mutation: 22 strains or lines available

References

• Original: J:87872 Maeno H, et al., Comparison of mice deficient in the high- or low-affinity neurotensin receptors, Ntsr1 or Ntsr2, reveals a novel function for Ntsr2 in thermal nociception. Brain Res. 2004 Feb 13;998(1):122-9
• All: 5 reference(s)