Lsm4^{Gt(geo)G101Ref}
Gene trapped Allele Detail

Summary

• Symbol: Lsm4^{Gt(geo)G101Ref}
• Name: LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated; gene trap G101, Reinhard Fassler
• MGI ID: MGI:3029428
• Synonyms: G101
• Gene: Lsm4 Location: Chr8:71125898-71131402 bp, + strand Genetic Position: Chr8, 34.15 cM
• Alliance: Lsm4^{Gt(geo)G101Ref} page

Mutation origin

• Mutant Cell Line: G101
• Germline Transmission: Earliest citation of germline transmission: J:59997
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector Type: gene trap
• Mutation details: A gene trap vector inserted 4bp upstream of exon 2, resulting in an abnormal fusion transcript consisting of the first exon of the endogenous gene fused to the lacZ gene of the gene trap vector. (J:59997)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lsm4 Mutation: 77 strains or lines available

References

• Original: J:59997 Hirsch E, et al., Peri-implantation lethality in mice lacking the Sm motif-containing protein Lsm4. Mol Cell Biol. 2000 Feb;20(3):1055-62
• All: 1 reference(s)