Fhl2^tm1Chen
Targeted Allele Detail

Summary

• Symbol: Fhl2^tm1Chen
• Name: four and a half LIM domains 2; targeted mutation 1, Ju Chen
• MGI ID: MGI:3029431
• Synonyms: Fhl2^tm1Juc, SLIM3^-
• Gene: Fhl2 Location: Chr1:43162234-43236144 bp, - strand Genetic Position: Chr1, 22.33 cM
• Alliance: Fhl2^tm1Chen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:64807
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A lacZ gene and neomycin selection cassette were inserted into the endogenous gene such that the lacZ gene would be expressed under the control of the endogenous promoter elements. Northern blot analysis confirmed that no wild-type transcript was expressed from this allele. (J:64807)

Expression

In Mice Carrying this Mutation:	5 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fhl2 Mutation: 16 strains or lines available

References

• Original: J:64807 Chu PH, et al., FHL2 (SLIM3) is not essential for cardiac development and function. Mol Cell Biol. 2000 Oct;20(20):7460-2
• All: 15 reference(s)