Hnrnpc^{Gt(U3His)4A4Rul}
Gene trapped Allele Detail

Summary

• Symbol: Hnrnpc^{Gt(U3His)4A4Rul}
• Name: heterogeneous nuclear ribonucleoprotein C; gene trap 4A4, H Earl Ruley
• MGI ID: MGI:3029723
• Gene: Hnrnpc Location: Chr14:52310834-52341462 bp, - strand Genetic Position: Chr14, 26.79 cM
• Alliance: Hnrnpc^{Gt(U3His)4A4Rul} page

Mutation origin

• Mutant Cell Line: 4A4
• Germline Transmission: Earliest citation of germline transmission: J:62141
• Parent Cell Line: D3H (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: U3NeoSV1
• Mutation details: The endogenous locus was disrupted by the insertion of retroviral gene trap vector containing Beta-geo. The construct was inserted into intron 1, and disrupted normal splice patterns of this gene. (J:62141, J:151685)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  PSTVU01.4A4	CL440625 ; (MGI Seq Detail)	plasmid rescue	Chr14:52341126-52341677 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  134 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hnrnpc Mutation: 60 strains or lines available

References

• Original: J:62141 Williamson DJ, et al., hnRNP C is required for postimplantation mouse development but Is dispensable for cell viability. Mol Cell Biol. 2000 Jun;20(11):4094-105
• All: 2 reference(s)