Rce1^tm2.1Kim
Targeted Allele Detail

Summary

• Symbol: Rce1^tm2.1Kim
• Name: Ras converting CAAX endopeptidase 1; targeted mutation 2.1, Edward Kim
• MGI ID: MGI:3032503
• Synonyms: Rce1^delta
• Gene: Rce1 Location: Chr19:4672619-4675669 bp, - strand Genetic Position: Chr19, 4.07 cM
• Alliance: Rce1^tm2.1Kim page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:87958
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The coding region was deleted via cre-mediated recombination of flanking loxP sites in the germline. (J:87958)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rce1 Mutation: 14 strains or lines available

References

• Original: J:87958 Bergo MO, et al., On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy. J Biol Chem. 2004 Feb 6;279(6):4729-36
• All: 2 reference(s)