Tbx1^nmf219
Chemically induced Allele Detail

Summary

• Symbol: Tbx1^nmf219
• Name: T-box 1; neuroscience mutagenesis facility, 219
• MGI ID: MGI:3032517
• Synonyms: nmf219
• Gene: Tbx1 Location: Chr16:18399729-18409412 bp, - strand Genetic Position: Chr16, Syntenic
• Alliance: Tbx1^nmf219 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Hypomorph)
• Mutation: Single point mutation
• Mutation details: This ENU-induced A to G point substitution at coding position 653 results in the replacement of aspartic acid with glycine at amino acid 212, which is a highly conserved residue in the T-Box DNA binding domain. (J:278988)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	30 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbx1 Mutation: 36 strains or lines available

References

• Original: J:87349 JAX Neuroscience Mutagenesis Facility, Heritable mouse mutants from JAX NMF ENU Mutagenesis Program. MGI Direct Data Submission. 2004-7
• All: 2 reference(s)