Sgk3^fz-ica
Spontaneous Allele Detail

Summary

• Symbol: Sgk3^fz-ica
• Name: serum/glucocorticoid regulated kinase 3; iasi congenital atrichia
• MGI ID: MGI:3032837
• Gene: Sgk3 Location: Chr1:9868332-9971070 bp, + strand Genetic Position: Chr1, 2.08 cM
• Alliance: Sgk3^fz-ica page

Mutation origin

• Strain of Origin: Swiss albino

Mutation description

• Allele Type: Spontaneous
• Mutation: Transposon insertion
• Mutation details: A spontaneous mutant identified in the Genetics Laboratory at Faculty of Veterinary Medicine, Iasi, Romania, this mutant was determinied to be an allele at the fz locus via complementation analysis. Reverse transcription-polymerase chain reaction (RT-PCR) analysis of mutant DNA detected an excessively long mRNA that was shown to be the product of abnormal RNA splicing consequent to insertion of a class II retrotransposon into the third intron. (J:125551)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sgk3 Mutation: 30 strains or lines available

References

• Original: J:88408 Cirlan MV, A new mutation at the fuzzy (fz) locus. MGI Direct Data Submission. 2004
• All: 5 reference(s)