Crhq1^C57BL/6J
QTL Variant Detail

Summary

• QTL variant: Crhq1^C57BL/6J
• Name: compensatory renal hypertrophy QTL 1; C57BL/6J
• MGI ID: MGI:3033048
• QTL: Crhq1 Location: Chr11:98574481-98574636 bp Genetic Position: Chr11, cM position of peak correlated region/allele: 62.4 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: C57BL/6J

Variant description

• Allele Type: QTL

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:49069

A significant difference was observed between inbred strains C57BL/6J (smaller) and DBA/2J (larger) in compensatory renal hypertrophy (CRH) allowing for the mapping of the quantitative trait (QTL) in male mice from BXD (C57BL/6J x DBA/2J) recombinant inbred RI strains. As association of the QTL with markers on mouse Chromosome 11 was observed with a peak LOD score of 15.8 at marker D11Mit14.

References

• Original: J:49069 Zidek V, et al., Quantitative trait loci for compensatory renal hypertrophy in the mouse. Biochem Biophys Res Commun. 1998 Jul 30;248(3):473-5
• All: 1 reference(s)