Im6^Bioz:BP1
QTL Variant Detail

Summary

• QTL variant: Im6^Bioz:BP1
• Name: immunoregulatory 6; Bioz:BP1
• MGI ID: MGI:3033078
• Synonyms: high antibody responder, Im6^H
• QTL: Im6 Location: Chr12:113860337-113860525 bp Genetic Position: Chr12, cM position of peak correlated region/allele: 62.22 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: Bioz:BP1

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers increased antibody response compared to Bioz:MP1. (J:37251)
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:37251

High(H) and Low(L) antibody responder lines of Biozzi mice were used in mapping Im loci. (H x L)F1 x L mice were informative in mapping Im6 with D12Nds2.

References

• Original: J:37251 Puel A, et al., Toward genetic dissection of high and low antibody responsiveness in Biozzi mice. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14742-6
• All: 1 reference(s)