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Tshp10LG/J
QTL Variant Detail
Summary
QTL variant: Tshp10LG/J
Name: tooth shape 10; LG/J
MGI ID: MGI:3033615
QTL: Tshp10  Location: unknown  Genetic Position: Chr11, cM position of peak correlated region/allele: 42.94 cM
QTL Note: genome coordinates based on the marker associated with the peak LOD score
Variant
origin
Strain of Specimen:  LG/J
Variant
description
Allele Type:    QTL
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:76126

76 polymorphic microsatellite markers at an average distance of 27.5 cM were screened in 535 (SM/J x LG/J)F2 animals to identify QTLs associated with tooth development. Parental inbred strain LG/J exhibits larger body size compared to SM/J. Tshp9 and Tshp10, QTLs influencing tooth shape, mapped to mouse Chromosome 11. The Tshp9 interval is centered around 1.5 cM at D11Mit62 and the Tshp10 interval spans 28 cM - 40 cM on chromosome 11 near D11Mit15. Tshp9 and Tshp10 exceed the P<0.001 significance threshold of LOD=4.185.

References
Original:  J:76126 Workman MS, et al., Analysis of quantitative trait locus effects on the size and shape of mandibular molars in mice. Genetics. 2002 Apr;160(4):1573-86
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory